Modality 04

Antibody Drug Conjugates (ADC)

Targeted cytotoxic therapeutics combining antibody specificity with potent payloads through optimized linker chemistry and site-specific conjugation.

Antibody-Drug Conjugate (ADC) structure with antibody, linker, and cytotoxic payload

Overview

Integrated antibody, linker, and payload engineering.

We characterize DAR distribution, conjugation site heterogeneity, and stability using high-resolution mass spectrometry and orthogonal bioanalytical methods to advance ADC candidates with confidence.

Computational design and optimization of Antibody-Drug Conjugates