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Modality 01

Monoclonal Antibodies

Monoclonal antibodies are Y-shaped proteins built from two identical heavy and light chains. Their variable regions form a paratope that binds a single antigen with high affinity and specificity, while the constant Fc region drives immune effector functions such as ADCC, CDC, and complement activation — making mAbs a precise, versatile, and clinically validated therapeutic modality.

Monoclonal antibody structure and regions

We design and engineer highly specific monoclonal antibodies optimized for targeted therapy, developability, and clinical translation.

Computational design and optimization of monoclonal antibodies